Title: Senior Microbiologist, Influenza Branch
Institution: Centers for Disease Control & Prevention
Dr. Tumpey is responsible for the rescue and characterization of infectious influenza viruses containing 1918 genes and for the investigation of the most appropriate countermeasures to prevent disease in the mouse model. Once recombinant viruses are rescued, Dr. Tumpey oversees animal pathotyping under the institutional guidelines of animal care and polices and practices outlined for BioSafetly Level 4 Laboratory. In addition, he is investigating whether some of the 1918 genes conserve sufficient avian characteristics to still be able to function in avian hosts. These studies are helping to define the genetic requirements for adaptation of an avian influenza virus to a human host.